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The neuroprotective mechanism of HDACi was linked with upregulation of expression of NGF, activation of TrkA phosphorylation, phospho-protein kinase B (p-AKT), NFB, and B-cell lymphoma 2 (Bcl-2) cell survival factors, while the downregulation of phospho-JNK, p75 neurotrophin receptor (NTR), and Bcl-2-associated X protein apoptosis factors (Wu et al., 2013) studied the effect of VPA, TSA, 4-phenyl butyric acid (4-PBA), and nicotinamide in astrocyte and dopamine neuron glial culture

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Preclinical studies of Nrp1 including antibody blockades and genetic knockout models have been shown to reduce tumor growth and progression in prostate, lung, and skin cancers [140]

Abraham, M

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and i.g.) could prevent, attenuate, and reverse gastric and liver lesions induced by chronic alcohol drinking in rats