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Semaglutide has a half-life of approximately 7 days, meaning your body clears roughly half the drug each week while maintaining steady-state therapeutic levels

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[DOI] [PMC free article] [PubMed] [Google Scholar] 32.Ayala J.E., Bracy D.P., James F.D., Burmeister M.A., Wasserman D.H., Drucker D.J