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While pharmaceutical options are still being researched, foundational cellular support remains a cornerstone of functional recovery

moderate ROS can sustain pro-survival pathways, whereas excessive ROS can exceed antioxidant capacity and trigger cell death ( Plant-derived polyphenols (phenolic acids, flavonoids, stilbenes, and related metabolites) ( in vitro effects often fail to translate into clinical effects because many phenolics exhibit poor solubility, instability, and rapid metabolism, which lead to low systemic bioavailability (e.g low levels in the bloodstream) and inadequate tumor exposure ( In this review, redox sensitization refers to a tumor-directed increase in oxidative pressure, or a reduction in tumor antioxidant buffering, sufficient to move malignant cells closer to an apoptotic or therapy-responsive threshold

Hasanuzzaman et al., 2014)

Gong L, Tang N, Chen D, et al

(1)These statements have not been evaluated by the Food and Drug Administration

ImmunoTargets and Therapy, Volume 14, pp.359382