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Physiology and metabolism of pathogenic neisseria: tricarboxylic acid cycle activity in Neisseria gonorrhoeae
Its proven to ease symptoms of nerve damage and lower the risk of diabetic retinopathy (eye damage) that can occur with uncontrolled diabetes ( Its believed that this effect is due to the powerful antioxidant properties of alpha-lipoic acid ( Though alpha-lipoic acid has been shown to aid blood sugar control, its not considered a complete treatment for diabetes
Itaconate promotes Nuclear Factor Erythroid 2-related Factor 2 (Nrf2) activation and, subsequently, an anti-inflammatory phenotype in macrophages [245]
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[DOI] [PMC free article] [PubMed] [Google Scholar] Mitani T