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More serious side effects, though rare, may include: Allergic reactions Hypoglycemia Changes in vision Pancreatitis Kidney failure Gallbladder issues Well go over everything you can expect at your weight loss evaluation and help you determine if semaglutide or tirzepatide are the best options to help you meet your weight loss goals

Gastroenterology 122 , 12481257 (2002)

Experiment 1: Semaglutide Sixteen rats (7 males and 9 females) were initially assigned in a counterbalanced manner to one of four treatment conditions: 0, 0.01, 0.03, or 0.1 mg/kg semaglutide