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343 According to a 2020 systematic review and meta-analysis that included 60 randomized controlled trials with a total of 4,129 patients, omega-3 fatty acid supplementation appeared to decrease the incidence of cardiovascular death by 55% in CKD patients on hemodialysis, though it did not appear to reduce mortality overall

Al-Owain M, Kaya N, Al-Shamrani H, Al-Bakheet A, Qari A, Al-Muaigl S et al

Orexin receptor antagonistsdrugs that inhibit the wake-promoting activity of orexinshave shown remarkable success in promoting sleep

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Beyond these results in vitro , several clinical studies have also highlighted the benefits of L-carnitine for oily skin

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