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We found a 18% reduction in GLP-1 sensitivity as measured by GLP peak :incretin effect ratio in carriers of p.S539W compared to non-carriers (0.69 0.05 vs

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Scientific investigations have examined the supportive use of silymarin alongside the following liver conditions: Liver stress caused by excessive alcohol consumption Non-alcoholic fatty liver disease (NAFLD) Liver fibrosis and cirrhosis (supportively, alongside medical treatment) Viral liver diseases such as Hepatitis B and C (as a complementary measure, not as a standalone therapy) Scientists describe the positive properties of silymarin as a "functional triad" acting in an anti-inflammatory, antioxidant and cell-protective manner