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Furthermore, ferroptosis requires STAT3-mediated expression of lysosomal protein cathepsin B [168] and a recent study demonstrated the role of lysosomal cystine in modulation of sensitivity to ferroptosis [169]

Early symptoms include weakness, lightheadedness, and dizziness

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In cardiovascular health, for example, low GPx activity allows lipid peroxidation to inflame arteries, increasing risks of heart attacks and strokes