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This can be particularly beneficial for individuals with digestive disorders or those who struggle to absorb nutrients naturally

Inducing ferroptosis or treating with IFN- in Institute of Cancer Research (ICR) mice exacerbates the symptoms of SS, while inhibition of ferroptosis or the IFN- signaling pathway in non-obese diabetic (NOD) mice models alleviates both ferroptosis in the salivary gland and SS symptoms

PLoS Genet 6:e1001036

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Ruptured ferroptotic cells trigger innate immunity by releasing damage-associated molecular pattern molecules (DAMPs), such as heat shock proteins (HSPs) and oxidized lipids, upon tissue damage or tumor therapy ( Composed of B cells, T cells, and their secreted products, adaptive immunity is responsible for recognizing and clearing pathogens or abnormal cells specifically and forming immune memory ( 2.1 Macrophages Macrophages, which form a pivotal element of the innate immune system, are imperative for several facets of inflammatory processes, phagocytosis of debris, and tissue repair ( Figure 2 )