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They help your pancreas release insulin when your blood sugar is high and lower another hormone called glucagon, keeping your blood sugar from going up too much

The process takes about 30 seconds and is virtually painless

Best before: See base

Nausea, constipation, and reduced appetite for favorite foods are common but typically mild

For Maximum Weight Loss: Tirzepatide (22.5% average loss) Semaglutide (14.9% average loss) Distant third: Phentermine-topiramate (9.3% loss) For Best Value: Compounded semaglutide ($97 per pound lost) Compounded tirzepatide ($112 per pound lost) Others significantly worse For Most Patients: Compounded semaglutide or compounded tirzepatide provide the best combination of effectiveness, tolerability, and affordability