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Further elucidation of these mechanisms may enhance our understanding of pyroptosis in DOR and aid in the development of natural product-based therapies targeting pyroptosis-related factors

10.31662/jmaj.2020-0005 JMA J

Sinclair EM, Drucker DJ

The use of assisted reproductive technologies (ART) such as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) can bypass some of the natural selection mechanisms that would prevent sperm with damaged DNA from fertilizing an egg, potentially leading to long-term consequences for the offspring

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