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It is plausible that GSTs serve two distinct roles in the development of drug resistance via direct detoxification as well as acting as an inhibitor of the MAP kinase pathway

doi:10.1016/j.taap.2012.05.010 Yao WB, Zhao YQ, Abe T, Ohta J, Ubuka T (1994) Effect of N -acetylcysteine administration on cysteine and glutathione contents in liver and kidney and in perfused liver of intact and diethyl maleate-treated rats

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