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10.1016/j.exer.2005.08.011 56 SarchahiA
While insomnia is not listed as a common side effect in clinical trials, some users experience changes in sleep quality or timing during the first weeks of treatment
[xvi] - Kidd PM
10.3389/fphar.2024.1335814 37 HuangB.AnH.ChuJ.KeS.KeJ.QiuY.et al (2025)
"Our results indicate that further research into semaglutide's use will need to be further investigated through randomized clinical trials so alternative drugs can be tested as potential treatment for this debilitating illness," Xu said
Dosing schedule (per Health Canada ): Starter dose: 0.25 mg once weekly for the first 4 weeks Increase: 0.5 mg after Week 4, if tolerated Further titration: Up to 1 mg or more, depending on your treatment plan The gradual increases, occurring every 4 weeks, are designed to minimize side effects and promote a safer, more sustainable treatment response
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