GLP-1 receptor agonists frequently cause nausea, vomiting, diarrhoea, constipation, and abdominal discomfort, particularly during the initial weeks of treatment
The combined number of participants in the two studies was small, 173, consisting of 93 children in one study and 80 adults in the other
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Efficacy of tenapanor in treating patients with irritable bowel syndrome with constipation: A 26-Week, placebo-controlled phase 3 trial (T3MPO-2)
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Researchers may compare its triple-receptor agonist profile with single- or dual-receptor agonist profiles to better understand differences in receptor activation, intracellular signaling, and physiological responses