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Additionally, curcumin regulates IL-6 (interleukin-6), IL-8 (interleukin-8), tumor necrosis factor-alpha, and COX-2 expressions, which are responsible for the progression of inflammation in the body (7, 52, 53)

Pyruvate kinase M2 (PKM2) is also inhibited by oxidation [41], which enhances flux through the pentose phosphate pathway and oxidative stress resistance

Autophagy is required for glucose homeostasis and lung tumor maintenance

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Lane M, Maybach JM, Gardner DK: Addition of ascorbate during cryopreservation stimulates subsequent embryo development