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SIRT3 attenuation or ablation is associated with accelerated development of several diseases of aging 45

Validation by targeted amplicon sequencing of a subset of predicted SNVs and small indels showed an accuracy of 90% (sensitivity 86%, specificity 98%) (Supplementary Notes, Supplementary Tables 3 and 4)

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There are three types of inflammation: (a) cytokine-based, (b) eicosanoid-based, and (c) free-radical-based