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Characterized by the removal of the N-terminal amino group from the cysteine residue at position 1, this modification grants the molecule superior resistance to enzymatic degradation

This buildup is thought to trigger downstream effects, including the formation of tau-containing neurofibrillary tangles, due to an imbalance between A production and clearance

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Tierney LM, et al

Two people on 10 mg can have very different results

[DOI] [PubMed] [Google Scholar] 9.Bulun S.E., Yilmaz B.D., Sison C., Miyazaki K., Bernardi L., Liu S., Kohlmeier A., Yin P., Milad M., Wei J