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The simplest compound in the series ( 14 , Table 1), was identified as 3-methylindolyl glutathionyl disulfide (ISSG

According to the FDA-approved prescribing information, the primary pharmacological mechanism of this medication is glycaemic control

As there is no systemic absorption to the body, effects of other body processes are minimized

The meta-analysis then calculated any differences in effects on HbA1c (glycated haemoglobin, a measure of blood sugar control), body weight, and also the risk of adverse events

The injection process stretches the skin and triggers brief inflammation as the body responds to the foreign substance entering the tissue layer

10.1002/anie.201508464