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Curcumin has been found to significantly decrease the miRNA expression levels of miRNA 155 ( P = 0.002), miRNA 138 ( P = 0.024), and miRNA16 ( P = 0.0001) [189]

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We report an age-related accumulative pattern of late endosomes in both genotypes, which could be related to a deficiency in the turnover of the bound GTP state of Rab7 due to low GTP levels

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Recently, a hypothesis has been proposed that may also implicate pathogens in the development of Downs syndrome (DS) and related Downs syndrome Alzheimers disease (DSAD) (Norins, 2022)

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