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More recently, analysis using the Broad Institutes Connectivity Map database identified GHK as one of the top two compounds (from 1,309 bioactive molecules screened) recommended for study in aggressive metastatic colon cancer models, with GHK upregulating expression of numerous caspase genes and DNA repair genes associated with anti-cancer activity
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[DOI] [PubMed] [Google Scholar] 79.Silva R.O., Freitas Filho J.D., Freitas J
Conclusions and outlook This review summarizes the characteristics of iron metabolism in humans, the association between obesity and ferroptosis, and the neuroimmune regulation associated with obesity and ferroptosis
Therapeutic Potential Due to its high affinity for the IGF-1 receptor and the benefits that activation of this receptor can provide, it has been investigated for its ability to treat: Wounds and Injuries: IGF-1 LR3 supports the regeneration of tendons and nerves after injury, potentially speeding recovery and reducing scar formation