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GLP-1s may act as a vaccine for addiction, potentially leading to a significant public health impact, even without intentional use for addiction treatment

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Not only do NETs and their components (histones, DNA, and myeloperoxidase) directly damage endothelial cells, but their synergistic effects with oxLDL or native LDL further enhance endothelial-to-mesenchymal transition (EndMT), leading to endothelial cell dysfunction and promoting neovascularization, which influences AS progression [285]