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164 Acetaldehyde dehydrogenase 2 (ALDH2) is a nuclear-encoded aldehyde oxidase present in the mitochondrial matrix

Variants in FTO (the fat-mass and obesity-associated gene), GLP1R (the GLP-1 receptor gene targeted by every GLP-1 compound), MC4R (a melanocortin receptor central to satiety and energy balance), and TCF7L2 (a transcription factor linked to glucose homeostasis and GLP-1 secretion) map the metabolic terrain any compound acts on

doi: 10.2147/DDDT.S378976 62 ZhangD-DChenQ-QYaoL