does semaglutide have anti inflammatory properties & Inflammation: Clinical Evidence & Biomarker Context – PlexusDx Frontiers | Glucagon-like peptide-1: a

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BAP1 regulates different mechanisms of cell death

The genes affected by semaglutide included markers of inflammation and plaque stability that are associated with leukocyte recruitment [e.g., interleukin-1 (IL-1) receptor antagonist, IL-6, monocyte chemoattractant protein (CCL2), OPN], leukocyte adhesion [selectin E, vascular cell adhesion molecule-1 (VCAM1)], leukocyte extravasation and plaque stability (e.g., MMP3, MMP13, CCL2), and plaque rupture and hemorrhage (CD163)

R., Liu, L

Ongoing and future clinical trials are expected to further define the cardiovascular role of GLP-1 RAs, expand their therapeutic indications, and solidify their place in the evolving landscape of cardiovascular care

Curr Protein Peptide Sci 23(5):310320