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Name: is glp 1 tirzepatide vs Semaglutide | Understanding The Differences Semaglutide & tirzepatide are transforming
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doi:10.1136/bmjdrc-2016-000258

& Gao, B

In 2005, the FDA approved a synthetic version of exendin-4 called exenatide (Byetta)

Last reviewed: June 19, 2026 Last updated: June 19, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Certain situations require extra caution

A 2024 survey of 340 obesity medicine specialists (Fitch et al., Obesity Science & Practice ) found that 68% restart at 2.5 mg, 24% start at 5 mg, and 8% individualize based on patient history