PlexusDx also offers alternative approaches like oral tirzepatide ($349/month) for patients preferring needle-free options, compounded semaglutide injection ($189/month starting), and dual-compound GLP-Squared formulations combining both medications
The median (IQR) dose normalized trough concentration increased from 0.4 ng/mL/mg (0.30.6) on day 1 to 0.9 ng/mL/mg (0.61.4) on day 7 and 1.1 ng/mL/mg (0.61.6) on day 14
Each region takes its own approach to protect consumers through different labeling rules and safety standards
Important framing: none of the three has the kind of large-scale Western randomized controlled trial data that compounds like rapamycin have
Tirzepatide has the most extensive published literature, with FDA approval, multiple completed Phase 3 trial programs (SURMOUNT, SURPASS), and extensive real-world evidence
other medications on worsening mental health, defined as a composite of psychiatric hospitalization, sick leave from work for more than 14 days for psychiatric reasons, hospitalization due to self-harm, or death by suicide. Secondary outcomes included worsening anxiety, worsening depression, self-harm and worsening substance use disorder
