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Excessive iron generates ROS through the Fenton reaction, which further aggravates mitochondrial dysfunction and forms a progressive vicious cycle

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According to Maselli, Contraves most common side effects include (9): Headache Nausea or vomiting Constipation Dizziness Fatigue Sleep issues Dry mouth Maselli says you can dodge most of these side effects by starting a low dose of Contrave and gradually build to the maximum dose (two tablets twice daily

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