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Further research is required to characterize the biological mechanisms associated with NNMT inhibition and the broader implications of these findings

In primary culture of satellite cells, the LASSS-treated HGF (Figure 1f, bars 9 and 11 , at 5 ng/ml without or with exposure to peroxynitrite, respectively) normally activates satellite cells to a level equivalent to the positive control ( bar 2 ) as revealed by BrdU-incorporation assay

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The peptide is hi ghly stable in gastric juice, allowing for potential oral bioavailability, and can also be administered via injection in preclinical studies

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