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The ominous octet (Defronzo model) includes: decreased muscle glucose uptake, increased hepatic glucose output, impaired incretin effect, alpha-cell hyperglucagonemia, increased renal glucose reabsorption (SGLT-2 upregulation), increased lipolysis (adipose), decreased central satiety signaling, and decreased beta-cell insulin secretion

Nutrient-Rich Diet Consuming a diet rich in essential nutrients is paramount for optimal platelet production

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Because oral supplements are absorbed less effectively, you need to take them far more frequently than you would need an injection