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The study showed that heparin-based targeting can be designed to have a greater half-life, further relying on antibodies with exposed antigens, whose expression is constantly modified by successive generations of the parasite ( Plasmodium berghei which contained a conserved region, as a consensus heparin sulfate proteoglycan-binding sequence attached to the distal end of a lipid-polyethylene glycol bioconjugated, was prepared by the incorporation into phosphatidylcholine liposomes, reflecting favorable in vitro results ( Antibody-Functionalized Drug Delivery Systems for Targeted Therapy in Schistosomes Infection Antibodies are mostly IgGs or their fragments and have ability to recognize and interact virtually with any molecular target with high affinity and high specificity

Neuron 84 , 275291 (2014)

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Mechanisms of cytotoxicity of nicotine in human periodontal ligament fibroblast cultures in vitro

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