Colleen McCabe, PharmD, BCOP, and Lindsay Mundy, PharmD, BCOP, led an engaging exploration of the benefits and potential pitfalls with the use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in an oncology setting in their presentation, GLP-1s in Oncology: Miracle, Misdirection, or Missed Opportunity
In a study of children with obesity compared to healthy peers, there was no significant link between hormone levels, including GLP-1, and gastric motility regardless of obesity or GERD status, suggesting childhood obesity does not yet cause physiological changes in gut motility or GLP-1 signaling effects on gut motility [122]
Weekly self-injection under the skin (subcutaneous) Gradual dose increase to minimize side effects Regular follow-ups to monitor progress and adjust treatment Support with nutrition and lifestyle coaching Common Side Effects Nausea Diarrhea or constipation Mild stomach discomfort Side effects usually lessen after the first few weeks
Mechanisms of hepatoprotection by GLP-1RAs as immune-metabolic modulators 4.1
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The system is equipped with 405 nm, 485 nm, 561 nm, and 642 nm laser lines, as well as a 980 nm IR laser and xyz piezo (Piezoconcept) for active sample stabilisation
