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Promotes Cognitive and Neurological Function Preclinical human neural models 8 have shown that IGF-1 supports neurogenesis and neuronal repair
Study selection, eligibility criteria, and data extraction Reviewers underwent training at each step of the process, and a pilot screening was conducted to ensure consistency in applying the eligibility criteria
FIGURE 2 The pMET protein levels peak at P7P14 in the neocortex, a period corresponding to synaptogenesis and dendritic outgrowth, and are downregulated during the 3rd post-natal week, between P14 and P17, when pruning and functional synapse maturation occur (Eagleson et al., 2016)
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For example, glycolysis inhibitors can impair ATP production, preventing caspase-dependent apoptosis as metabolic dormancy [151]