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Effect of GLP-1 receptor agonists on bone mineral density, bone metabolism markers, and fracture risk in type 2 diabetes: a systematic review and meta-analysis

10.1016/j.ijpharm.2024.123991

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Cardiovascular outcome trials have established benefits for specific agents: the LEADER trial for liraglutide, SUSTAIN-6 for injectable semaglutide, and REWIND for dulaglutide demonstrated reduced risk of major adverse cardiovascular events in patients with type 2 diabetes

Loss of muscle can be detrimental to metabolism and aging, affecting strength, mobility, decreasing metabolic rate, increasing risk of insulin resistance, diabetes, cardiovascular health, and overall quality of life

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