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Strengthens Immune Function - Low glutathione levels have been directly linked to weakened immune response

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doi: 10.1016/j.atherosclerosis.2022.03.024 110 TakedaHMurakamiSLiuZSawaTTakahashiMIzumiYet al

However, in resistant patients, oxidative stress causes a conformational change in Keap1, leading to the release of NRF2, which translocates to the nucleus and binds to antioxidant response element (ARE), activating the expression of downstream antioxidant genes, including GPX4, NQO1, HO-1 and SOD1 [33], and promoting the synthesis of GSH, as illustrated in Fig

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