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5.3 Potential mechanisms of dietary fiber affecting depression (1) Mood regulation mediated by SCFAs produced via gut microbiota fermentation Dietary fiber cannot be digested and absorbed by the human body but can be partially or fully fermented by gut microbiota (122)

The first group was kept as a negative control (without injection), the second (positive control) was injected with 0.1 mL saline solution 0.9%, while the third, fourth, and fifth groups were injected with Fe 3 O 4 -NPs, Cu-NPs, and ZnO-NPs, respectively, at a concentration of 30 g/egg 37,38

Minimal decreases in plasma aldosterone were observed after administration of valsartan

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Mice were group-housed, up to five per cage, in a specific pathogen free facility verified through viral and bacterial tests (IDEXX Bioanalytics)

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