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Lancet Diabetes Endocrinol 3(5):367381 van Bommel EJM, Muskiet MHA, Tonneijck L, Kramer MHH, Nieuwdorp M, van Raalte DH (2017) SGLT2 inhibition in the diabetic kidneyfrom mechanisms to clinical outcome

The subcutaneous route delivers the medication directly into the adipose tissue, from which it is absorbed into the systemic circulation independent of gastric contents or digestive processes

The good news is that typical supplemental doses are considered safe and arent linked to an increased risk of miscarriage

When to choose the 5mg vial Choose 5mg for the initial dose escalation phases, weeks 1 through 8, when you are dosing at 0.25mg or 0.5mg weekly

Yes, rare cases have been reported

10.1007/s11357-013-9514-2 28 LangmeadB.SalzbergS