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Usage of protease inhibitors was also suggested in treating MDMA-related neuronal damage, since the MDMA-induced neuronal damage is mediated through the time-dependent degradation of structural proteins such as cytoskeletal II-spectrin and microtubule-associated tau, leading to cytoskeletal damage [74]

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324 Furthermore, the gut microbiome characteristics of patients with NAFLD remission after bariatric surgery manifested as higher abundance of Bacteroides , Akkermansia , and multiple genera of SCFA-producing Clostridia (such as Blautia , Faecalibacterium )

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