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Metformin, the first-line treatment for T2D, induces vitamin B12 deficiency through calcium-dependent antagonism of the intrinsic factor-B12 complex absorption in the terminal ileum, with studies showing a 13% increased risk of deficiency per year of use and higher prevalence in patients using metformin for more than 4 years at doses exceeding 1000 mg daily [158]

However, its potential for weight loss has gained significant attention

10.1038/s41467-017-01403-9 40 Perez-BurgosA.MaoY

By identifying the root causes of your symptoms and addressing them with integrative treatments, I can help improve your quality of life

Maintaining a healthy weight can be challenging for those with hemophilia, especially when joint damage, pain, or bleeding concerns make some types of physical activity harder

54.3 years Younger 80.7% vs