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Description

This modification uniquely induces structural rearrangements associated with amyloidogenic conversion, in contrast to other post-translational modifications on Cys10, such as, S-cysteinylation or S-glutathionylation, that do not significantly alter the native fold [22]

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IR-Tac Pharmacokinetic Data DISCUSSION For drug formulations that exhibit modified release characteristics and prolonged absorption, t 1/2z may not adequately predict accumulation or the time required to reach steady state

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