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Tirz GLP2 (60 mg) utilizes tirzepatide , a synthetic peptide that activates both GLP1 and GIP receptorshormonal pathways central to regulating appetite, improving metabolism, and supporting blood sugar control

However, these patients often have severe comorbidities, altered nutritional status, and multiple medication interactions that complicate tirzepatide use

(139) showed that paeoniflorin could reduce bone destruction and inflammatory infiltration of joints in CIA mice and inhibit osteoclast differentiation

1) The common effector assumption

PMCID: PMC11475329