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10.1016/j.plaphy.2015.11.001 159 TravensoloR

If nausea is problematic, your prescriber may extend the time between dose increases

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Finally, T5 , analogous to T1 where hydroxyl groups are substituted by methoxy groups, results in an IC 50 = 40.02 M, suggesting that hydrogen bonds (provided by the hydroxyl groups) are more favorable than the hydrophobic interactions (supported by the methoxy groups) in mushroom tyrosinase inhibition (Supplementary Fig