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10.3390/cancers13102478 191 UrsiniF.MaiorinoM

Anti-Inflammatory Activity: Reduces TNF-alpha-induced IL-6 secretion in human dermal fibroblasts, with proposed anti-inflammatory benefits

Abstract Silent information regulator (SIRT) has distinctive enzymatic activities and physiological functions to control cell-cycle progression, gene expression, and DNA stability by targeting histone and non-histone proteins

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Human studies suggest potential benefits for longevity, cardiovascular health, and physiological function in older adults [4]