the other three are cysteine, homocysteine, and taurine
You can read the pilot clinical trial in full for the methodology
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Homozygous TT genotypes of G2677 and C3435 polymorphisms, as well as TT, CTT, and TTT haplotypes of the ABCB1 gene, are significantly associated with the development of therapeutic resistance to VPA
Among those test subjects with the lowest serum levels of Acetyl-L-Carnitine, scientists noted a history of childhood abuse, neglect, poverty and/or exposure to violence, in addition to exhibiting severe, treatment-resistant symptoms
This will include an analysis of clinical data and reports from patients, offering insight into how widespread this issue might be