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The efficacy of semaglutide, tirzepatide, and retatrutide in treating obesity may be promising for patients with POMC-MC4R pathway deficiency

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In these cases, all patients maintained glycaemic control, with HbA1c levels remaining below 7.5%

Elevated glucose levels can activate immune cells and trigger the release of inflammatory cytokines, making chronic hyperglycemia a key driver of inflammation in diabetes [29]

Synergy between inhibitors of androgen receptor and MEK has therapeutic implications in estrogen receptor-negative breast cancer