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Mol Psychiatry 29 , 25872598 (2024)

For the primary outcome (CRP), funnel plots comparing GLP-1 RAs to placebo and to other oral antidiabetic drugs (OADs) showed relatively symmetrical distributions, suggesting a low risk of significant publication bias ( Figures 2 , 3 )

Clinical trials have provided limited insight into the long-term effects, as the longest trials spanned less than six years in adults and about one year in adolescents

Over a median follow-up of 118 [50, 121] months, the cumulative incidence of PLC was 8.6% vs

However, recent research has suggested the drugs potential may be more diverse than just helping with diabetes treatment