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The MS was operated in the multiple reaction-monitoring (MRM) mode using the following parameters: MRM transitions: m/z 208.2 122.0 [collision energy (CE) 12 eV] for felinine, m/z 265.1 178.9 (CE 11 eV) for MBCG, m/z 394.2 179.0 (CE 17 eV) for MBG, and m/z 250.1 121.9 for N -acetylfelinine
Absence of human clinical studies: despite thirty years of animal research, no large randomized controlled human clinical study has been published on BPC-157
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