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One nuance worth knowing: increased polyamine flux was actually framed as part of the benefit in the original obesity work, because cycling polyamines through synthesis and breakdown burns energy

[20] It can also be injected intravenously for the purpose of treating cyanide poisoning, as the hydroxyl group is displaced by cyanide, creating a non-toxic cyanocobalamin that is excreted in urine

However, weight loss was never the primary focus of BPC-157 research

Niu J, Ma B, Shen J, Chi H, Zhou H, Lu Z, Lu F, Zhu P (2024a) Structure-guided steric hindrance engineering of Devosia strain A6243 quinone-dependent dehydrogenase to enhance its catalytic efficiency

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