Wegovy comes in five dosage strengths, including two maintenance dosage strengths, which are part of a structured titration schedule designed to support long-term treatment for both of the drugs indications
They originally treated diabetes, but because they act on powerful metabolic levers, they've proved useful against obesity, heart disease, sleep apnea, potentially addiction and now cancer
Mechanism of Action Glucagon-like peptide-1 (GLP-1) is a member of the incretin family (gastrointestinal hormones released after meals that increase insulin secretion during periods of hyperglycaemia)
However, some more serious risks are non-arteritic anterior ischemic optic neuropathy, a form of permanent eye stroke, and diabetic retinopathy, a worsening of existing diabetic eye disease
Sitagliptin (10 mg/kg/day) treatment decreased the expression of proinflammatory cytokine genes IL-1 and TNF- in kidney of diabetic ZDF rat [25]
Yes, they can cause side effects from skin irritation or issues with adhesives