Both longitudinal melanonychia and subungual bleeding have a range of benign and malignant causes (see Table 4)
Founded in 1988 and headquartered in Tarrytown, New York, Regeneron has developed and commercialized drugs for diseases in several areas, such as oncology, eye diseases, allergic and inflammatory diseases, pain, cardiovascular disease and infectious diseases
References: Based on STEP 1 (Wilding et al., NEJM 2021) and SURMOUNT-1 (Jastreboff et al., NEJM 2022) trials
Olaparib, for instance, is an FDA-approved inhibitor of the enzyme poly ADP ribose polymerase (PARP) which can efficiently kill BRCA mutant tumor cells, a successful synthetic lethality based targeting strategy used in breast cancers and ovarian cancers (165)
doi: 10.1016/j.biopha.2020.111014 144 ZhaiZ.NiuK
The platform is positioned for people who are already on a GLP-1 medication - Ozempic, Wegovy, Mounjaro, Zepbound, or similar - and want a structured way to track what happens to their body composition, specifically their lean muscle tissue, while the medication is driving weight loss
