Brand Performance Overview Key Findings Several brands met chemical criteria, but few met microbiological/pyrogen criteria
Diabetes Care (2012) 35:4857
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Theres evidence suggesting these drugs reduce an enzyme in the body that metabolizes alcohol, which means a little bit of alcohol goes a lot further, making it easy to over-drink
The difference seems to come from how GLP-1 drugs slow gastric emptying, delaying the movement of alcohol from the stomach to the small intestine, where its absorbed
During this process, neutrophil extracellular trap (NET) release activates mitochondrial autophagy imbalance, causing ferroptosis and excessive ROS generation (Chu et al., 2023)