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Research suggests that the ventromedial hypothalamus (VMH) plays a central role in leptin-induced glucose uptake in skeletal muscle, brown adipose tissue (BAT), and heart tissue

Try to finish eating at least two to three hours before bed

However, for patients with contraindications or intolerance to incretin-based therapy, continued use of basal insulin may remain the safer choice

Clinical trials conducted by Eli Lilly, the manufacturer of tirzepatide, found that fatigue affects approximately 5% of people taking the 5mg dose, 6% on the 10mg dose, and 7% on the 15mg dose

This can lead to faster weight gain potentially 1+ pound per week which can be appealing if youre trying to put on size quickly

They might even have some metastases that are small and stable, and I want to know if we should give them this drug or not